Measurement during Fibrinolytic Therapy

Fibrinolytic therapy for parapneumonic empyema during pregnancy

Pneumonia and parapneumonic complicated effusion during pregnancy is uncommon but poses potentially serious risks to both mother and fetus. Enzymatic debridement of the pleural cavity with fibrinolytic agents is a noninvasive option that can facilitate drainage and prevent the need for surgery. Herein, we describe the cases of two pregnant women with parapneumonic empyema who were successfully ...

Measurement of Spontaneous Fibrinolytic Activity.

The spontaneous fibrinolytic activity of blood is due to a labile activator which appears to be stabilized by adsorption to fibrin (Fearnley and Tweed, 1953; Fearnley, 1953; Flute, 1960). At present activator activity can be measured only indirectly through its conversion of plasminogen to plasmin which in turn causes fibrinolysis. Whatever method is used it is essential to cool the blood sampl...

Concurrent antiplatelet and fibrinolytic therapy.

In patients who have myocardial infarction with STsegment elevation, rupture of an atherosclerotic plaque leads to platelet adhesion, activation, and aggregation, with subsequent vessel occlusion due to thrombus formation. In these circumstances, the most effective pharmacologic reperfusion regimen is concurrent fibrinolytic therapy and platelet inhibition. The marked benefit of such a combinat...

Fibrinolytic Therapy of Coronary Thrombosis.

Fibrinolytic Therapy in Acute Stroke

Acute ischemic stroke is a major cause of morbidity and mortality in Europe, North America, and Asia. Its treatment has completely changed over the past decade with different interventional approaches, such as intravenous trials, intra-arterial trials, combined intravenous/intra-arterial trials, and newer devices to mechanically remove the clot from intracranial arteries. Intravenous thrombolys...